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FDA Approves New Drug Treatment for Chronic Weight Management, First Since 2014. U.S
Potential Research Applications: IGF-1 receptor binding affinity and cellular signaling studies Cellular growth and differentiation pathway research Binding protein resistance and in vitro stability mechanism models Growth factor analog activity and structure-function investigations For laboratory research only
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458 Specifically, in response to Frataxin deficiency, the activation of iron-responsive element binding protein 1 (Fe-S protein) increases cellular iron uptake, with the iron being translocated into mitochondria via mitochondrial iron transporters in an attempt to compensate for impaired Fe-S cluster biogenesis
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