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glutathione's antioxidant activity may dampen this response Mechanism 4: Thyroid Hormone Metabolism Support Thyroid hormone conversion - the transformation of inactive T4 (thyroxine) to active T3 (triiodothyronine) - is performed by iodothyronine deiodinase enzymes (DIO1, DIO2, DIO3), which are selenoproteins that depend on the glutathione/thioredoxin antioxidant system for their activity and regeneration
To track the peptides effects on tissue repair, analyze biomarkers like: Collagen deposition Angiogenesis levels Inflammatory cytokine profiles Additionally, consider functional assessments, like gait analysis or strength tests in animal models
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Awad S1, Lobo DN: Metabolic conditioning to attenuate the adverse effects of perioperative fasting and improve patient outcomes
I outline my tried and tested protocols for doing all of the above in my book Hashimotos Protocol , and you can read more about the importance of finding your root cause in my article
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