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The SURPASS-CVOT trial, where dulaglutide at the dose of 1.5 mg/week or at the highest tolerated dose, is the comparator, has a distinctive design from the other trials: the primary endpoint is the time to the first manifestation of any major adverse CV event (MACE), defined as myocardial infarction, stroke or CV death
For cardiovascular applications, this monitoring becomes particularly important given the potential for blood pressure and heart rhythm effects
Coverage, formulary restrictions, and out-of-pocket costs for sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 receptor agonists in the medicare part D program
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
Use the labeled tirzepatide concentration for all conversion calculations
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