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Back to Journals Diabetes, Metabolic Syndrome and Obesity Volume 19 Gastrointestinal Adverse Effects of GLP-1 and Dual GLP-1/GIP Receptor Agonists: A Comprehensive Update in Diabetic and Obese Populations Authors Ylmaz N , Bastemir M Received 27 November 2025 Accepted for publication 13 January 2026 Published 30 January 2026 Volume 2026:19 584175 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 4 Editor who approved publication: Dr Halis Akturk Nimet Ylmaz, 1 Mehmet Bastemir 2 1 Department of Gastroenterology, SANKO University Faculty of Medicine, Gaziantep, Turkey
Strategies that may help manage gastrointestinal side effects include: Dietary modifications: Eating smaller, more frequent meals rather than large portions can reduce nausea and discomfort
Combined use increases side effects
Different pens presentation are available and are sold under brand names Ozempic and Wegovy, and have been approved to have a high impact on weight loss for overweight and obese people
So far, the strongest studies have been observational
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