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Representative agentsincluding the B7-H3CD3 BsAb MGD009 and the EGFRvIIICD3 BsAb AMG596have entered phase I/II testing, providing preliminary signals of CNS tolerability and antitumor activity
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Organic Anion-Transporting Polypeptide Substrates (Oatp) Theoretically, concomitant use might increase the effects and adverse effects of OATP substrates
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Previous observations also highlighted the stimulatory role of IGF-2 in the proliferation [18] and expression of progesterone and estradiol in luteinized granulosa cells in humans [19, 20]
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