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Ashley SN, Nordin JML, Buza EL, Greig JA, Wilson JM (2018) Adeno-associated viral gene therapy corrects a mouse model of argininosuccinic aciduria

The sequence is proline-rich, with three consecutive prolines followed by a fourth at position eight, and that conformationally constrained backbone is the usual structural explanation offered for the resistance

Krol MB, Galicki M, Gresner P, Wieczorek E, Jablonska E, Reszka E, Morawiec Z, Wasowicz W, Gromadzinska J

Still, the increases in cortical and total BMC were due to increased bone dimensions, whereas the volumetric BMD was unchanged