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15 In the SURPASS-1 study, tirzepatide monotherapy at increasing doses of 5, 10, and 15 mg resulted in significant weight loss of 7, 7.8, and 9.5 kg, respectively, at week 40 in patients with T2DM, compared with a 0.7 kg decrease with placebo
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However, there are few reports on the influence of -3 on pregnancy rate, and no major side effects were reported from the included studies
Nausea is the most common GI side effect
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