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In whole-cell current clamp experiments, hyperpolarizing or depolarizing current pulses (500 ms, from 10 to 30 pA in 5-pA steps) were injected into neurons to determine input resistances or trigger action potentials
t = 60 min) were modestly lower after Met (60 min)
GLP-1s also may lead to decreased free fatty acid concentrations
Chronic use of NSAIDs like ibuprofen is a leading cause of gastric ulcers and GI bleeding
Because the hydrophilicity of the drug inhibits its transport process across cell membranes, metformin must rely on transporters to actively transport in and out of cells (Hardie et al., 2012)
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