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Some other possible side effects that may occur include: Headache Stomach pain Fatigue Constipation Dizziness Heartburn or indigestion Low blood sugar (hypoglycemia) Bloating Gas Mood changes Although rare, they can rarely cause serious and sometimes life-threatening adverse effects such as: Severe allergic reaction Pancreatitis Gallstones Kidney problems Worsening vision (diabetic retinopathy) in type 2 diabetics Heart rate changes Suicidal thoughts or behaviors Increased risk of thyroid cancer Bowel obstruction (a blockage that keeps food from passing through your intestines) These are not all of the possible adverse effects of these medications
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The non-coded amino acid residues incorporated at positions 2, 20, and 13 provide resistance to enzymatic degradation while maintaining receptor-binding affinity across all three target receptors
Reported side effects in published literature are limited to injection site reactions (redness, mild swelling) and transient drowsiness, likely related to melatonin pathway activation
