A 2006 Achilles-detachment study by Krivic and colleagues in the same journal applied BPC-157 intraperitoneally once daily at 10 g/kg, 10 ng/kg, or 10 pg/kg for 30 days in rats and reported that tendon-to-bone tissue, which did not heal spontaneously in saline controls, recovered with BPC-157 treatment, with directionally improved load-to-failure, stiffness, Young's modulus, and collagen organization at days 121, including in animals where healing had been impaired by 1 mg/kg 6-methylprednisolone though the abstract does not report numeric effect sizes or p-values
This work now shows a direct line from biochemical and biophysical understanding of protein interactions to an inhibitor, says Kritzer, who was not involved in the research
10.1007/s10545-005-4417-8
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Cultural attitudes toward pleasure, work, and achievement influence how patients interpret and respond to motivation-related interventions
