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In addition to the high dosage of metformin (1,500 mg/day), a GLP-1 receptor agonist (Liraglutide, Victoza, Novo Nordisk, Denmark) was added for appetite reduction
Modulates Neuroendocrine Activity DSIP has been shown to influence neuroendocrine regulation, interacting with hormonal systems that control stress, recovery, and metabolic balance
Clinical data consistently shows that tirzepatide produces greater weight loss than semaglutide in head-to-head comparisons
Novinscak et al
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