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Abbreviations ACC: American College of Cardiology AHA: American Heart Association AN: Anorexia Nervosa APGAR: Adaptability, Partnership, Growth, Affection, and Resolve BED: Binge Eating Disorder BES: Binge Eating Scale BIQLI: Body Image Disturbance Questionnaire BMBF: Federal Ministry of Education and Research BMI: Body Mass Index BN: Bulimia Nervosa CBT: Cognitive Behavioral Therapy DATO: Dutch Audit for Treatment of Obesity EASO: European Association for the Study of Obesity EMA: The European Medicines Agency FDA: U.S

The most immediately relevant risk relates to glucose metabolism

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At the end of the trial, seven of the participants had significantly increased bowel movement frequency, reduced constipation symptoms, and improved quality of life, with no adverse events (Queralto 2013)