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The Future of Glutathione Research Scientific interest in how Glutathione works is growing, with studies exploring its role in everything from neurodegenerative diseases to metabolic disorders

Numerous in vitro studies show that ITCs induce apoptosis via both intrinsic and extrinsic pathways (108)for instance, through caspase activation (109), mitochondrial dysfunction (110), and oxidative stress generation (111)

These findings further suggest that at acute time points, both GCLC and NRF2 are dispensable to the liver