Many commercial preparations contain additional ingredients such as: Sorbitol or mannitol sugar alcohols used as sweeteners in some tablets that can cause osmotic diarrhoea when consumed in larger quantities, though the amounts in typical supplements are usually too small to cause symptoms alone [13] [14] Binding agents and fillers including lactose, which may cause symptoms in people with lactose intolerance, though tablet quantities are typically small Other additives various excipients that some individuals may be sensitive to The dose and frequency of supplementation may also influence tolerability
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Bacteriostatic vials allow multiple entries, but each entry must be done with a new sterile syringe/needle to avoid introducing pathogens
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In November 2023, the FDA added BPC-157 to its list of substances that cannot be used in compounding under the Federal Food, Drug, and Cosmetic Act, citing insufficient safety data for human use 3