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lise - Richmond Vials were well-sealed and properly labelled

The compound therefore functions as a positive modulator of an existing growth factor system rather than as an independent agonist, which is the proposed explanation for its reported potency: it amplifies a signal already present rather than supplying a new one

2019;doi:10.1183/16000617.0012-2019

Impact of HER2 heterogeneity on treatment response of early-stage HER2positive breast cancer: phase II neoadjuvant clinical trial of T-DM1 combined with pertuzumab