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Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases
Certain GLP-1 drugs, including semaglutide and tirzepatide, are FDA-approved for specific uses such as treating type 2 diabetes and, in certain cases, chronic weight management
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Inhibition of this enzyme can lead to pellagra, which, in these cases, may present with cerebellar signs, myoclonus, and ataxia (5, 12, 55)
Cortistatin sleep studies used intracerebroventricular administration, limiting practical applicability Anti-Inflammatory Co-Benefits Cortistatin Cortistatin has potent anti-inflammatory activity demonstrated in models of IBD, sepsis, and arthritis
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