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The Triple Agonist Mechanism and Weight Loss Huberman described retatrutide as a triple agonist of the GLP-1, glucagon, and GIP receptors, and noted that it is sometimes referred to as "GLP-3." He made a striking claim about the weight loss data: "In a phase three clinical trial in humans, it caused up to one-third loss of body weight

Importantly, monitoring and regular medical consultations can help manage these side effects effectively

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Glucomannan, psyllium, inulin, beta-glucan, and resistant maltodextrin form viscous gels that slow gastric emptying and blunt postprandial glucose