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Coverage in thinning areas may improve
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Dose adjustment and close follow-up may be needed, especially in moderate to severe chronic kidney disease
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Every day it absorbs substantial forces while walking, climbing stairs, exercising, changing direction, and lifting weight
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Oxidative Stress May Increase In animal models, sleep deprivation has been associated with a 2.5-fold increase in MDA (a marker of lipid peroxidation) and a 67% reduction in phosphatidylcholine, suggesting heightened oxidative injury and membrane damage (Chang et al., 2008
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