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Metabolism-dependent neutrophil cytotoxicity of amodiaquine: a comparison with pyronaridine and related antimalarial drugs
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Lactate dehydrogenase, creatine kinase, and -hydroxybutyrate dehydrogenase levels in myocardial zymograms of MBL-treated 4T1 tumor-bearing mice showed no significant increase when compared to the liposomal formulation of MXT-treated group (ML), indicating that MBL has a clear advantage in reducing MXT-induced cardiac toxicity
11 The well-known mechanism for p70S6K1 to promote survival is that p70S6K1 phosphorylates mouse double minute 2 (MDM2) leading to polyubiquitination and degradation of p53, and thus represses p53-dependent apoptosis
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