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The deficiency was more severe than expected People with advanced B12 deficiency, especially with neurological symptoms, often feel rough at the start of treatment because the underlying problem was significant
The stiffness of the repair tissue also increased to nearly 9 N/mm with TB-500, compared to approximately 6 N/mm in the controls
NICEs guideline covers recognising and managing B12 deficiency in adults, including deficiency linked to autoimmune gastritis
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