The purity and integrity of complex were assessed by SDS-PAGE with at least 5% SDS to ensure solubilization of components
Indications and Usage for B-12 Compliance Injection Cyanocobalamin is indicated for vitamin B12 deficiencies due to malabsorption which may be associated with the following conditions: Addisonian (pernicious) anemia Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacteria overgrowth, total or partial gastrectomy Fish tapeworm infestation Malignancy of pancreas or bowel Folic acid deficiency It may be possible to treat the underlying disease by surgical correction of anatomic lesions leading to small bowel bacterial overgrowth, expulsion of fish tapeworm, discontinuation of drugs leading to vitamin malabsorption (see DRUG INTERACTION), use of a gluten-free diet in nontropical sprue, or administration of antibiotics in tropical sprue
Some practitioners hold patients at 10 mg if weight loss trajectory is satisfactory, reserving higher doses for plateaus
By reducing NTBI, LPI and LCI pools, iron chelators may influence enzyme functions depending on iron, and influence ROS homeostasis
PMID 7175933
