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GLP-1s & Surgical Timing Because these medications slow gastric emptying, they must be paused before any surgery

The study also linked GLP-1 medicaiton to a reduction in oxidative stress, which is closely tied to aging and neurodegeneration

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Oral peptides, by contrast, face sequential degradation barriers: gastric pH (1.53.5) denatures tertiary structure, pepsin cleaves peptide bonds at aromatic amino acids, and intestinal proteases (trypsin, chymotrypsin) fragment any remaining sequence before it crosses enterocytes