A serious problem of MS in the identification of metabolites is ion suppression, which is a kind of matrix effect and is mainly caused by the different volatility of metabolites, due to their different nature and structure, which in turn affects the output of the number of ions in the gas phase reaching the detector and eventually leads to errors in the quantification of the analysis (Annesley, 2003
For someone weighing 100kg, thats 15-25kg lost over one year, roughly 110-240 per kg lost over the course of a year
Otras series muestran resultados similares 25, 26
British Journal of Nutrition, 111 (7), 11471161
Wishart, Increased micronutrient requirements during physiologically demanding situations: review of the current evidence