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Dietary adjustments are often the first line of self-management: Eat smaller, more frequent meals rather than large portions Avoid high-fat, greasy, or heavily spiced foods, which can exacerbate loose stools Reduce intake of foods known to cause wind, such as beans, cruciferous vegetables, and carbonated drinks If constipation is the predominant symptom, increase soluble fibre gradually sudden large increases in fibre can worsen bloating and discomfort Stay well hydrated, particularly if experiencing diarrhoea, to prevent dehydration Timing and lifestyle considerations can also make a meaningful difference

Nanocrystal suspensions of poorly water-soluble GLP-1 analogs are also under investigation to increase dissolution rates and promote lymphatic absorption

Peptides aren't all administered the same way

Set realistic weight loss goals

Frequently asked questions How long does GLP-1 constipation last