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These effects were observed in multiple tissue compartments including brain, liver, and erythrocytes (Khavinson et al., Gerontology, 2007)

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While high-dose B12 is generally safe, its still important to use supplements thoughtfully and pay attention to any unusual symptoms

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Interestingly, one study noted no difference in the findings of esophageal cancer in patients with Barretts esophagus and high-grade dysplasia with the use of jumbo biopsy forceps compared with standard biopsy forceps