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Approximately 90% of the drug is rapidly inactivated by plasma pseudocholinesterase , while only about 10% reaches the neuromuscular junction (NMJ)

LipRSV formulations were prepared according to parameters defined by dynamic light scattering (DLS), which measured polydispersity index (PDI), hydrodynamic radius (RH), and zeta potential (PZ) (de Castro et al

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As such, individuals from the Kahemba region were recruited based on prior diagnosis of konzo by expert phenotyping of this disease, who were participants in the long-term clinical trials aimed at altering cassava processing to reduce konzo