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Additionally, ALCAR raised the transcription of Grm2 gene encoding for the mGlu2 receptor via increasing the levels of acetylated H3K27 bound to the Grm2 promoter and gaining the acetylation of NF-KB-p65 subunit

The tug-of-war between semaglutide (GLP-1 only) and tirzepatide (GLP-1 + GIP) isn't just about efficacyit's rewriting how we view metabolic medicine

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GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE -/- mice