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A critical caveat: thymosin beta-4 is upregulated in many metastatic cancers, facilitating tumor-cell migration to distant sites.20 This theoretical cancer-promotion risk is a serious safety consideration that distinguishes TB-500 from other compounds in this article

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Therefore, we do not claim direct causality between an individuals prior B12 test and their hospitalization episode, although a significant correlation exists in large populational level between vitamin B 12 deficiency and hospital admissions for cardiovascular, hematological, neurological, psychological, and gastrointestinal diseases