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The researchers conducted a retrospective cohort study to examine the association between use of GLP-1 RAs and the risk for dementia in patients with CKD stage 3 or later, compared with use of dipeptidyl peptidase-4 (DPP-4) inhibitors

These effects are typically temporary and go away on their own

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Previous diagnoses and medications Out of all 45,326 incident patients included within the entire period, 85.8% had at least one of the selected cardiovascular and metabolic diagnoses recorded in primary care or hospitals during 5 years before being dispensed their first GLP-1 RA, whereas 14.2% had not been given any of these diagnoses (Fig