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The lack of HrpA/HrpB TPS in the gonococcus would explain why the gonococcus remains predominantly confined within a vacuole during cellular infection, unlike the meningococcus, which is able to escape, and why the meningococcus, after reaching the cytosol, induces pyroptotic pathways during cellular infection, a phenomenon not described for the gonococcus
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Subsequent studies and patents from the same group of researchers showed that a 15 amino acid peptide derived from the N-terminus of BPC, now known as BPC 157, has many of the same effects as the entire protein
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