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GLP-1RAs appear to favor pro-survival responses in -cells, heart, brain and bone where the IGF-1/IGF-1R system appears to play an important role

The authors of an older 1993 overview published in the Journal of Physiology-Paris explain that after the gastric juice peptide BPC was isolated, a 15-amino-acid fragment believed to be essential for its functioning was identified this was BPC-157

Brains were quickly extracted and sliced (300 m) for whole cell recordings in current-clamp and voltage-clamp mode

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