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Four weeks at 0.5mg uses 2mg
Furthermore, in Calcr Cre rats injected with adeno-associated virus (AAV)-DIO-hM3Dq-mCherry in the AP, essentially all mCherry-identified AP Calcr Cre neurons contained CALCR but not GLP1R immunoreactivity (we lack a reliable reporter allele for Calcr Cre in rats
"It would not establish an approved indication, standardized dose, demonstrated efficacy, or an FDA-reviewed safety profile." For FDA approval, the peptides would need to undergo large and rigorous randomized controlled trials to validate their efficacy and safety
The data supporting the results will also be available on reasonable request from the corresponding author and C.M
Traditionally the dorsogluteal (DG) muscle was used for IM injections but this muscle is in close proximity to a major blood vessel and nerves, with sciatic nerve injury a recognised complication (Small, 2004)
