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Chenglai Xia, [email protected] These authors have contributed equally to this work This article was submitted to Cardiovascular and Smooth Muscle Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

At the time, Eli Lillys Trulicity was the only GLP-1 on the market

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This activation leads to the conversion of ATP (adenosine triphosphate) to cyclic AMP (cyclic adenosine monophosphate or cAMP)