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The variants EEHV-1A and -1B are most associated with severe disease, with EEHV-1A accounting for most HD fatalities 8
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TLK286: phase I dose escalation trial in patients with advanced malignancies
It cannot distinguish between properly folded and misfolded peptides
Clinical studies show efficacy at concentrations as low as 0.01 nM, with optimal results at 1100 nM (Maquart et al., 2015)
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