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When food remains in the stomach for extended periods, there is increased opportunity for acidic gastric contents to reflux into the esophagus, especially when lying down or bending over
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doi: 10.1038/mp.2012.141, 56 GriffinM.BaileyK
Note that 2/3 of the weight lost by the participants was regained within a year of stopping treatment with semaglutide
In contrast to Ozempic, berberine does not slow down GI motility
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