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Diabetes 64 , A528 (2015)
10.1007/s40258-019-00494-3 44 PratleyR
(2017) Synthetic Growth Hormone-Releasing Peptides: A Historical Appraisal of Cytoprotective Effects PMC5392015 Deghenghi R et al
To establish the importance of the NEP-derived metabolite GLP-1(2836) to the overall cardiovascular biology of GLP-1, we used sacubitril, a pharmacological inhibitor of NEP, and assessed in vitro cAMP accumulation in caSMCs, as well as functional LVDP recovery in an ex vivo Langendorff model of IRI
The Danish companys diabetes expertise with GLP-1s like Victoza provided crucial regulatory and clinical experience that competitors lacked
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