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These metabolic improvements were accompanied by a significant reduction in food and caloric intake (Figures 1D, E)

[5] The ratios are inconsistent across species, which is itself telling, but in every case the subcutaneous dose required was substantially higher than the intravenous one

Loss of Appetite: A reduced interest in food is a common effect of semaglutide, sometimes making it difficult to meet nutritional needs

This article originally appeared on USA TODAY: Weight-loss drugs draw thousands of lawsuits alleging serious harm Reporting by Chris Kenning and Austin Fast, USA TODAY / USA TODAY USA TODAY Network via Reuters Connect