37 A preliminary study has reported that the mSHMT enzyme allows for functional redundancy in cases where activity of the cSHMT enzyme is inhibited, and is up-regulated in cells lacking cSHMT during DNA replication and repair cell phases
Simultaneously targeting tissue transglutaminase and kidney type glutaminase sensitizes cancer cells to acid toxicity and offers new opportunities for therapeutic intervention
Maiorino M, Aumann KD, Brigelius-Floh R, Doria D, van den Heuvel J, McCarthy J, Roveri A, Ursini F, Flohet L (1995) Probing the presumed catalytic triad of selenium-containing peroxidases by mutational analysis of phospholipid hydroperoxide glutathione peroxidase (PHGPx)
This approach works but is less elegant than optimized delivery systems
Effects of Compression Garments on Muscle Strength and Power Recovery Post-Exercise: A Systematic Review and Meta-Analysis