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3.1 Shortacting GLP1 receptor agonists 3.1.1 Beinaglutide BN is a recombinant human GLP-1(7-36) acid, obtained by genetic engineering technology, and the amino acid sequence of its active component is the same as that of GLP-1 in the human body
The duration of 7 weeks was chosen based on a prior human study in CFS patients showing that the greatest improvement against fatigue took place between 4 and 8 weeks (30) and rodent studies showing effects on brain serotonin levels already after 21 25 days of carnitine supplementation (32, 33)
32 A recent systematic review and meta-analysis supporting these findings also showed that GLP-1 RA use was not associated with cholecystitis or gallstones in overweight/obese individuals without diabetes
Its benefits also include a skin brightening effect
& Huc, L
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