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Whether this dose should be maintained for long-term treatment is currently being investigated in the BOND study, which evaluates the effects of 12 months of benfotiamine treatment (300 mg twice daily) on morphometric, neurophysiological and clinical parameters in individuals with T2D and mild-to-moderate symptomatic DPN [73]

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These reactions may include: severe gastrointestinal issues pancreas inflammation gallbladder disease kidney damage allergic reactions increased heart rate eye complications in people with diabetes suicidal thoughts and behaviors food or liquid entering the lungs when under general anesthesia or deep sedation Animal studies have indicated that the use of Wegovy during pregnancy may affect a developing fetus, and that the therapy is excreted in breast milk

Consistency and pairing with DHT blockers improves outcomes