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Two other mu class members, GST M5-5 and the polymorphic GST M1-1, gave specific activities of 58 and 57.8 mol min 1 mg 1 , respectively

The least-squares mean percentage change in body weight from baseline was -7.2% in the 1 mg group, -12.9% in the 4 mg group (starting at 2 mg), -17.1% in the combined 4 mg groups, -17.5% in the combined 8 mg groups, and -17.5% in the 12 mg group, compared with -1.6% in the placebo group

Gabapentin impacts mood and cognition by controlling the release of gamma-aminobutyric acid (GABA) in the brain, which results in calming effects

Both therapies converge on the same cellular signaling pathways, and their combined effect may be greater than the sum of their parts

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