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Robust filtering of the candidate list for hits near undetectable in the negative controls revealed the bait TMEM55B as the top hit (Fig
10.1016/j.fshw.2023.03.029 162 WangJ.ZhangY
Research trials have seen positive outcomes after ingesting this supplement regularly over several weeks, especially when taken alongside antioxidants such as vitamin C
We challenged these results from cathepsin D activity-based probes by assaying proteolytic cleavage of DQ-BSA, a quenched fluorophore coupled to BSA taken up by endocytosis that emits fluorescence upon lysosomal proteolysis
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