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While they can be a helpful tool in a weight loss journey, it's crucial to remember that they work best when combined with a balanced diet and regular exercise
Eli Lilly reported its first Phase 3 readout (TRIUMPH-4) in December 2025, showing about 28.7% weight loss at 68 weeks, and a larger pivotal trial (TRIUMPH-1) in May 2026 showing about 28.3% weight loss at 80 weeks in 2,339 participants
It is considered an investigational compound and is typically sold by research chemical suppliers under the label for research purposes only
Lee WD, Pirona AC, Sarvin B, et al
Some of its key functions include energy production, aiding in the creation of new DNA strands, and supporting the breakdown of homocysteine, an amino acid that can potentially increase the risk of cardiovascular disease when elevated
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