For topical cosmetic use on intact skin , the answer from the available evidence is that systemic copper absorption is minimal
PMID: 35002520 Cell Death Discov Pregnane X receptor protects against age-related bone loss in males via PI3K/Akt-mediated inhibition of apoptosis
216 Furthermore, a randomized, double-blind, placebo-controlled trial in 65 hemodialysis patients reported that taking 1,200 mg, but not 600 mg, of CoQ10 daily for four months decreased oxidative stress (as indicated by a decrease in F2-isoprostanes)
Potential BPC 157 benefits include: Tendon and ligament repair support Joint and soft-tissue recovery Reduced inflammatory signaling Gastrointestinal mucosal support Wound-healing support Recovery from training-related irritation or overuse These effects distinguish BPC 157 from peptides primarily used for hormone modulation
Orian Shirihai, Ph.D., Associate Professor at Boston University School of Medicine, and Marc Liesa, Ph.D., a research associate on Shirihais team at Boston University School of Medicine.