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The effects of tirzepatide on body weight control have also been confirmed in non-diabetic individuals in the SURMOUNT-1 study, where treatment with tirzepatide 1015 mg was associated with an average weight loss of approximately 20% at 72 weeks, exceeding 25% in one third of the patients
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SLU-PP-332 operates by activating the PGC-1 transcriptional coactivator and estrogen-related receptor alpha (ERR), triggering gene expression that promotes mitochondrial proliferation, fatty acid oxidation, and circadian rhythm regulation
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