Multivariable linear regression analyses were performed to evaluate independent associations between treatment group and primary outcomes (% weight loss and HbA1c reduction at 6 months), adjusting for age, sex, baseline BMI, baseline HbA1c, and hepatosteatosis grade
Formulated for professional veterinary use, it helps maintain healthy heart, muscle, and weight functions
We are thankful to the NIH for the endorsement of our approach and up to $2M to support preclinical and IND-enabling studies towards the under-appreciated area of addiction
In summary, our data demonstrate that via GIP signalling linagliptin is able to retain its ability to improve glucose tolerance in mice devoid of Gcg -encoded peptides, including GLP-1 and oxyntomodulin (two targets of DPP-4 degradation)
Funding was provided by the Medical University of Biaystok, Poland (Grant No.: B.SUB.25.250)