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& Malik, A
Preclinical studies do not indicate direct or indirect harmful effects regarding pregnancy, embryonic/embryonic development, childbirth or postnatal development
The largest psychiatric safety meta-analysis to date found that GLP-1 medications were not associated with increased risk of serious psychiatric adverse events overall ( Pierret et al., JAMA Psychiatry, 2025 ), and a post-hoc analysis of the major semaglutide weight management trials found no differences in depression, suicidal ideation, or suicidal behavior compared to placebo ( Wadden et al., JAMA Internal Medicine, 2024 )
It may also help maintain smooth, hydrated, and naturally radiant skin
J., Johnson, G
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