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Tang-Christensen et al., 1998)

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120 In fact, the effect of -tocopherol seems to be dependent on tissue saturation with vitamin C, and both vitamins may function synergistically to provide optimal conditions for endothelial NO formation

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Many studies have investigated the potential correlation between genetic background and hypogonadal dysfunction in individuals with PWS, but no data have shown an impact of the various genetic defects (such as 15q11-13 paternal deletion, mUPD, or imprinting defect) on pubertal development and fertility (73, 203, 204)