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Alcohol is a diuretic, which means it makes your kidneys flush out more water than you're taking in

Biochemical Pharmacology, 2018

Such accumulation-related toxicity can involve multiple systems of the whole body, with clinical manifestations including chronic kidney disease, sensorineural deafness, chronic peripheral neuropathy, refractory anemia, and persistent cancer-related fatigue, which seriously impair the long-term quality of life and even affect the long-term survival outcomes of cancer survivors

During EMT, E-cadherin expression decreases, while N-cadherin expression increases

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