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Katzen, H

J Clin Invest 122: 388-402, 2012

What the Evidence Does NOT Show An honest comparison is defined as much by what it refuses to claim as by what it reports

Retatrutide is not approved for use during pregnancy and animal studies show fetal harm at therapeutic doses

In SURMOUNT-1, clinically significant hypoglycemia (glucose 48 hours), signs of dehydration (dark urine, dizziness on standing), sustained blood pressure readings above 150/95 mmHg, or new-onset confusion or myoclonus that could suggest serotonin excess from another drug added to the regimen